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Supposing you have learned your major and minor open chords, or at least some, I would like to begin by showing you how to use them.
Just as all notes in a chord need to harmonize, all chords in a group or progression of chords need to harmonize. To play a chord progression in harmony is called playing in key.
I will now list the chords of each major key.
G, C, D
C, F, G
D, G, A
E, A, B
A, D, E
B, E, F#
F, A#, C
So, if you wanted to create a chord progression in the key of C, you could play the major chords--C, F, G. You could play F, C, G. You could play, G, C, F. To play in any particular key, you don't need to start with the key chord. Chords in that key only need to be there.
Here is an example of a chord progression in the key of C.